Typical parkinsonism is among the neurological complications of GD (including type 1).3, 4 The neuropathology of GD brains includes the typical hallmarks of PD, such as cortical and brainstem Lewy bodies.5 Heterozygote carriers of GBA mutations also have an increased frequency of PD, and these mutations are the most common genetic risk factor for developing the disease.6–8. Here, GBA1 is linked to Parkinson disease.