MYCN and neuroblastoma: In some regions (for example, in the promoter regions of HIST1H3C and ACSS3) it was also possible to distinguish different DNA methylation profiles between MNA (IMR-32, LAN-2 and N206) and MYCN single copy (SH-SY5Y, SK-N-AS, CLB-GA and SJNB-1) NB cell lines (Additional file 2).