Furthermore, IL6 and IL8 levels at randomization were similar in all patients regardless of AKI (Figure3), whereas IL6 levels at 96 hours were significantly higher in patients with AKI [124.5 (51.7-213.9)pgl/ml vs 33.8 (19.8-138.9)pg/ml, p = 0.027] (Figure3) IL6 levels at randomization were much higher in patients who died [947 (351.7-1311.1) vs 198 (142.7-283.2), p = 0.007], while IL8 levels were slightly higher [197.1 (159.9-189.1) vs 87.9 (49.8-137.5), p = 0.046]. Here, CXCL8 is linked to acute kidney injury.