Meta-analyses suggested that the other three MYOC polymorphisms Y347Y, R76K, and R46X were not associated with increased risk of POAG, with summarized ORs of 1.20 (0.91–1.57), 0.86 (0.69–1.08), and 1.02 (0.61–1.70) (Table 2). Here, MYOC is linked to open-angle glaucoma.