TNFAIP3 and viral myocarditis: Here, our study found that intravenous injection in vivo with adenovirus expressed A20 (Ad-A20) 2 days before CVB3 inoculation could significantly decrease the expression of pro-inflammatory cytokines in cardiac tissues on day 4, 7, and 10 and protect mice against viral myocarditis, as demonstrated by invariant body weight, improved survival rate, less increased serological CK, CK-MB, cTnI levels and less myocardical inflammation.