Using concurrent genome-wide a-CGH and SNP-array-based LOH analyses, we show that CDC73- mutated parathyroid adenomas may have a rather distinctive genetic profile; most strikingly characterized by absence of any significant CNAs on chromosome 1, 11 or 13, while the parathyroid carcinomas displayed similar CNAs to those previously observed in parathyroid carcinomas. This evidence concerns the gene CDC73 and parathyroid gland carcinoma.