In this study, we aim to evaluate the association of 7 loci, which have not been evaluated in Japanese populations, with susceptibility to type 2 diabetes in a Japanese population: 1 single nucleotide polymorphism (SNP) in DUSP9 on chromosome X and 6 South Asian GWAS-derived loci–GRB14, ST6GAL1, VPS26A, HMG20A, AP3S2, and HNF4A. This evidence concerns the gene GRB14 and type 2 diabetes mellitus.