EGFR and neoplasm: The in vivo imaging results were correlated with the results of in vivo inhibition of tumor growth by As2O3 (Figure 4A), further indicating that feasibility of using NIR optical imaging method to noninvasively monitor the therapeutic effect and the inhibiting effect of As2O3 on tumor EGFR expression in vivo was also dose and time dependent, consistent with previous reported research [4].