IFNG and infection: The impaired ability of CANP366 to induce IFN-γ response after infection with X31 virus and the absence of anti-CAPA224 IFN-γ response after CA/E3/09 infection indicated the amino acid changes on the predicted CA/E3/09 NP366 and PA224 CD8 epitopes affects the generation of peptide specific CD8 T cells.