In the EPM, locomotive activity (i.e. closed arm distance) and the occurrence of anxiety-related behaviours (i.e. time in open arm, open arm entry ratio, and frequency of stretch attend postures) was similar in WT and Abca7−/− mice (p–values >.05 for all parameters investigated), indicating that Abca7 deficiency had no impact on EPM locomotion or anxiety (Table 2). The gene discussed is ABCA7; the disease is Anxiety.