PTX3 and pulmonary arterial hypertension: Mean plasma PTX3 concentrations in PAH patients were 4.40±0.37 ng/mL (range 1.18–14.11 ng/mL, median 3.83 ng/mL), compared with 1.94±0.09 ng/mL (range 0.39–4.60 ng/mL, median 1.78 ng/mL) in healthy subjects (Figure 1A).