TMEM37 and Familial prostate cancer: Real-time PCR analysis revealed that miR-370 expression was markedly increased in all five prostate cancer cell lines tested (Tsu-Pr1, PC3, DU145, 22Rv1 and LNCaP), compared to normal prostate epithelial (PrEC ) cells (Figure 1A), indicating that miR-370 is upregulated in prostate cancer cell lines.