Although association between endogenous GCL and GAGE proteins in human cells and tissues could not be investigated due to the lack of GCL antibodies suitable for immunocyto- and immunohistochemistry, GAGE proteins might have been expected to localize at the nuclear membrane in cancer cells lines demonstrated to express endogenous GCL by Western blotting (e.g. HeLa, HCT116, MZ2-MEL; Fig. 4). This evidence concerns the gene GMCL1 and cancer.