Third, we selected MDA as a oxidative stress marker and hs-CRP and IL-6 as inflammatory markers in the present study; further studies could select more sensitive markers of oxidative stress such as urinary 8-epi-prostaglandin F2α, plasma oxidized LDL or the ratio of reduced glutathione to oxidized glutathione and other important adipokines (such as tumor necrosis factor α, IL-1β, leptin, monocyte chemoattractant protein-1 or proteins of the renin angiotensin system) in subjects with MS. This evidence concerns the gene LEP and myeloid sarcoma.