CD4 and myelodysplastic syndrome: The results showed that both MDS-MSC and normal-MSC could efficiently generate CD4+CD25+Foxp3+Tregs from CD4+CD25-T cells (5.8%±0.5% for T cell alone, 12.2%±0.8% for MDS-MSC, and 11.7%±0.7% for normal-MSC) (Figure 4A).