CD4 and myelodysplastic syndrome: We found that there were no significant difference in the generation of CD4+CD25+Foxp3+ Tregs (4.6%±0.6% for T cell alone, 5.5%±0.6% for low-risk MDS-MSC, 7.1%±0.5% for high-risk MDS-MSC, and 4.9%±0.6% for normal-MSC) (Figure 5C).