IL1B and atherosclerosis: IL-1β may act on atherosclerosis with different biological functions such as stimulating proliferation of vascular smooth muscle cells and endothelial cells [49], [50], increasing expression of adhesional molecule from endothelial cells [50], modificating the endothelium to promote coagulation and thrombosis [51], stimulating the synthesis of fatty acid carrier protein by adipose tissue in vitro [52], promoting the production of some other pro-inflammatory factors such as IL-6, fibrinogen and C-reactive protein [45], [46].