This revealed fresh, subacute and old intraventricular, subependymal intraparenchymal as well as subarachnoid hemorrhages determined by the presence of vital erythrocytes, erythrophages, hemosiderophages and haematoidin pigment, respectively, in the brains of JAM-C−/− C57BL/6 mice with a hydrocephalus but not in brains of JAM-C−/− C57BL/6 mice without a hydrocephalus or in wild-type control mice (Figure 6). This evidence concerns the gene JAM3 and Hydrocephalus.