Utilizing mRNA extracted from the same tumor xenografts (systemic decorin treatment for 23 days at 10 mg/Kg) and that used for the microarray experiments, we performed qPCR as a method to validate stromal gene expression for Mrgpra2, Gucy1a3, Siglech, Ligp, Irg1, and Il1b (downregulated genes) and for Bmp2k, Cadm1, Hey1, Peg3, Brd4, Zc3hav1 (upregulated genes). The gene discussed is IL1B; the disease is neoplasm.