We also identified metafeatures comprising probe sets targeting genes previously studied in the context of AD (VSNL1, PPP2CA, CYP3A4 (see above)) and genes highlighted by the analysis in Gomez Ravetti et al. [5] (PTEN, MAPK1, COX6A1, GABRQ, FCAR, FZD5, PIP5K1C, SHANK2, CPT2). The gene discussed is SHANK2; the disease is Alzheimer disease.