Analysis of leukocytes in the melanoma tissue revealed that the percentage of CD11c+ Langerin (CD207) high dendritic cells (LCs, Langerhans cells) significantly increased in melanoma tissue of mice adoptively transferred with Cl-IB-MECA-treated CD8+ T cells (Figure 5B and C; black bar) compared with control mice (Figure 5B and C; white bar). The gene discussed is ITGAX; the disease is melanoma.