Consistent with these findings, postmortem studies demonstrated a significant reduction in tumor volume in Mφ-c-Myc-KO mice compared with control animals (Fig. 3B), and these differences occurred without alterations in circulating B and T lymphocytes or CD11b+ cells (neutrophils, eosinophils, and classical and non-classical monocytes) (Fig. 3C, D). This evidence concerns the gene MYC and neoplasm.