For example, the mean anti-GAD65 antibody titer in the controls was 2,700 LU (95% CI; 2,570–2,840) and was much lower than the T1D samples with a mean titer of 75,300 LU (95% CI; 34,100–117,000) (Figure 1A). This evidence concerns the gene GAD2 and type 1 diabetes mellitus.