When animals were immunized twice with bmDCs loaded with CD11c-scFv-IDRgag or control-scFv-IDRgag in one-week interval and challenged one week after the second immunization, at 4 days post infection (dpi) animals immunized with bmDCs loaded with CD11c-scFv-IDRgag were protected against splenomegaly induced temporarily in B6 animals infected with the high virus dose used in this experiment (Fig. 7A). Here, ITGAX is linked to Splenomegaly.