In conclusion, XPD Gln751Gln (CC) and Asn312Asn (AA) genotypes may seem to be more susceptible to gastric cancer in Asian population but not in Caucasian population, suggesting that Gln751Gln (CC) and Asn312Asn (AA) genotypes may be important biomarkers of gastric cancer susceptibility for Asian population, the assumption that needs to be further confirmed in future well-designed studies among different ethnicities. This evidence concerns the gene ERCC2 and gastric cancer.