Surprisingly, we also find that CSB-PGBD3 binds indirectly to TRE motifs (tumor promoting antigen response elements) recognized by AP-1 family (activating protein-1) transcription factors, as well as to motifs for the TEAD1 (TEA domain family member 1) and CTCF (CCCTC-binding factor) transcription factors. The gene discussed is FOS; the disease is neoplasm.