In case of ALL susceptibility, rs10821936 in ARID5B and rs17405722 in STAT3 showed a weak interaction (Interaction ratio (IR) = 0.15) and two SNPs in ARID5B, namely rs10821936 and rs4509706 showed a moderate redundancy (Redundancy ratio (RR) = 0.33). This evidence concerns the gene STAT3 and acute lymphoblastic leukemia.