Figure2 - (a) Intense and diffuse immunostaining of the tumor cells cytoplasm for Chromogranin, LSAB technique (400x); (b) – Diffuse immunostaining of the tumor cells cytoplasm for Synaptophysin, LSAB technique (200x); (c) – Immunostaining of the tumor cells cytoplasm for NSE, LSAB technique (200x); (d) - Rare Ki-67 positive neoplastic cells, LSAB technique, (400x). The gene discussed is ENO2; the disease is neoplasm.