Dogs from SRMA A (median 7.5%; range 5.2 to 11%), SRMA Th (median 6.3%; range 3.9 to 10.4%), Neopl (median 26.1%; range 8.9 to 35.8%) and Mix (median 7.5%; range 8.9 to 35.8%) groups showed a higher percentage of PMNs positive for TLR3 (P <0.05) in comparison to dogs with pyogenic infections (Pyo, median 2.4%; range 1.3 to 4.7%). Here, TLR3 is linked to infection.