In the whole cohort, eGFR was inversely associated and ACR was positively associated with CRP, IL-6, SAA, when adjusting for age, BMI, smoking, systolic and diastolic blood pressure, hypertension treatment, LDL-cholesterol, HDL-cholesterol, triglycerides, treatment with statin, ACE inhibitors, ASA, anti-inflammatory agents, diabetes, and previous cardiovascular disease (models A–C, Table 2). The gene discussed is CRP; the disease is cardiovascular disorder.