STAT3 and central nervous system cancer: Cediranib-treated NSC11 glioma cells also showed a significant elevation of p-STAT3 expression, with a mean percentage of p-STAT3-expressing cells of 16.2 + 4.8% (median 16.5; range 10.0 – 22.4; n=7; P=0.05) (Fig. 2D).