First-day urine sCD163 concentrations were significantly higher in the SIRS group (20 cases) (74.8 ng/ml; range: 47.9-148.3 ng/ml) compared with those in the sepsis group (40 cases) (31.9; 16.8-48.0 ng/ml, P < 0.001) (Figure1A). This evidence concerns the gene CD163 and systemic inflammatory response syndrome.