All patients with facial lymphoedema had multifocal exophytic oral HIV-KS lesions and their average CD4+ T-cell count at the time of oral HIV-KS diagnosis was 28 cells/mm3 (CD4+ T-cell counts were available for eight of the nine patients) compared to 133 cells/mm3 for those patients without such facial lymphoedema (Table 3). Here, CD4 is linked to lymphedema.