CD8A and neoplasm: The product, HSP70-HER-2-PCs containing both membrane-resident tumor peptides, HER-2 protein as a representative, and other antigenic peptides bound by HSP70, were able to induce tumor-specific CD8+ T cells with higher specificity against SKBR-3 cells than traditional HSP70-PCs and recombinant human HSP70-HER-2 protein complexes (Figs. 5 and 6).