DCN and breast carcinoma: As can be expected, several other studies supporting the antitumor and antimetastatic activity for decorin have been published (Biaoxue et al. 2011; Goldoni and Iozzo 2008; Hu et al. 2009; Reed et al. 2005; Shintani et al. 2008; Troup et al. 2003), and low levels of decorin have been found to be associated with a shorter progression time and poorer survival in lymph node-negative invasive human breast carcinomas (Araki et al. 2009; Troup et al. 2003).