ABCB1 and non-small cell lung carcinoma: Genetic polymorphisms in CYP3A4, ABCB1, ERCC1, ERCC2, and XPD1 were found to be associated with inter-individual differences in taxane response in NSCLC patients[9-11], while other variants in CYP2C8, CYP3A5 and ABCB1 were related to variability in taxane-mediated neurotoxicity[12,13].