Similarly, a meta-analysis of seven prospective studies [14] demonstrated that carriers of the KIF6 719Arg allele (Arg/Arg homozygotes and Arg/Trp heterozygotes), but not non-carriers (Trp/Trp homozygotes), were at an increased risk of CAD and received a significant benefit from statin therapy. Here, KIF6 is linked to coronary artery disorder.