“Well the alternatives are trying to improve the red cell production, so optimizing nutritional support, vitamin levels and iron and the other way is about EPO...but it doesn’t seem to have any other outcome benefit thus far...there isn’t all of data to support that practice...” (ICU 9)“I would like to see us take less blood for blood gases and things and prevent iatrogenic anaemia” (ICU 1). This evidence concerns the gene EPO and anemia (phenotype).