Heterozygous germline mutations in SDHA, SDHB, SDHC, and SDHD cause hereditary paragangliomas and pheochromocytomas [9], and germline mutations in SDHB and SDHC were found to be associated with gastrointestinal stromal tumors [4]. This evidence concerns the gene SDHB and hereditary pheochromocytoma-paraganglioma.