Heterozygous germline mutations in SDHA, SDHB, SDHC, and SDHD cause hereditary paragangliomas and pheochromocytomas [9], and germline mutations in SDHB and SDHC were found to be associated with gastrointestinal stromal tumors [4]. The gene discussed is SDHC; the disease is gastrointestinal stromal tumor.