A search of the Gene Expression Atlas (http://www.ebi.ac.uk/gxa/gene/ ENSG00000184489) showed that the expression level of PRL-3 was highest in CML among 950 human cancer cell lines covering 32 different types of cancers (Dataset code: E-MTAB-37), suggesting a potential role of PRL-3 in CML pathogenesis (Figure1A). The gene discussed is PTP4A3; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.