IL17A and colorectal carcinoma: As shown in Figure 3, concentrations of IL-17A and IL-23 were higher in CRA patients (IL-17A: 6.4 ± 0.8 pg/ml, P = 0.242; IL-23: 34.6 ± 4.4 pg/ml, P = 0.004 ) and highest in CRC patients (16.1 ± 2.5 pg/ml, P < 0.001; 55.2 ± 5.5 pg/ml, P < 0.001) as compared with healthy controls (5.0 ± 0.8 pg/ml; 18.6 ± 2.7 pg/ml).