CYBA and endothelial dysfunction: In this vein, we have shown for the same subgroup of postinfarction patients, risk associations connected with thrombogenesis using the A387P polymorphism of THBS4 (thrombospondin-4) [127]; for oxidative stress, a major cause of endothelial dysfunction, the C242T polymorphism of CYBA (p22phox) [101, 127].