More recently, Moharir et al. [20] retrospectively analysed the utility of FDG-PET/CT for tumor surveillance in 18 children with NF1, with the specific aims to determine its potential role in the identification of optic pathway gliomas (OPGs) that are likely to progress and in the identification of malignant change in preexisting PNF. This evidence concerns the gene NF1 and optic pathway glioma.