In accordance to a potentially neuroprotective function elicited by RF, Söderqvist et al. [86] reported increased serum concentrations of transthyretin (TTR), a molecule specifically sequestering Aβ peptide, among long term users of wireless phone, in both a cross-sectional study of 313 subjects using mobile phones and cordless phone, and in a provocation study on 41 people exposed for 30 min to 890-MHz GSM signal (1.0 WKg−1), suggesting that TTR might be involved in the RF-mediated benefits in AD mice. This evidence concerns the gene TTR and Alzheimer disease.