The majority of the top enriched pathways (adjusted P < 0.1) 15 DPP from both gene datasets are immune associated such as T cell receptor signalling pathway, cytokine-cytokine receptor interaction, natural killer cell mediated cytoxicity, PPAR signalling pathway, rheumatoid arthritis, graft-versus-host disease, allograft rejection and autoimmune thyroid disease (Table 1). The gene discussed is PPARA; the disease is rheumatoid arthritis.