According to the linear regression model, factors associated with fatigue were levels of pain (p < 0.0001), depression (p = 0.0017), appetite (p < 0.0001), drowsiness (p < 0.0001), well-being (p < 0.0001), shortness of breath (p < 0.0001), albumin level (p < 0.0001), and nausea status (p = 0.0001) (Table5). This evidence concerns the gene ALB and depressive disorder.