LAPTM4B and metastatic malignant neoplasm in the lymph nodes: LAPTM4B genotype (RR, 2.740, 95%CI, 1.549-4.846, P = 0.001) and lymph node metastasis (RR, 2.604, 95%CI, 1.368-4.955, P = 0.004) are also prognostic markers for disease-free survival in these patients (Table 3; P<0.05).