AKT3 and sarcoidosis: The most highly significant TCR-JS-CCR signature gene SNP in AAs was rs2131817 (P = 1.4×10−5) in AKT3, whereas in EA cases, the most significant SNP was rs7614488 (P = 7.8×10−7) in CBLB. Several TCR/JS/CCR signature gene SNPs, rs2953040 and rs6791765 in CBLB (Cas-Br-M, murine, ecotropic retroviral transforming sequence b) and rs2131817 in AKT3 were significantly associated with sarcoidosis in both EA and AA sarcoidosis cases (P<0.01) (Table S1).