SERPINE1 and melanoma: Curiously, the expression profile exhibited for the genes HSPB1 and SERPINE1 in Mel-2 and Mel-3 human metastases was noted for mouse cell lines representing pre-malignant melanocytes and non-metastatic melanoma cells (4C and 4C11− cell lines, respectively) in comparison to melan-a melanocytes (Figure 4B-4C, Figure 5C-5D).