BRCA2 and cancer: BRCA1/2, thus, accounts for 10 to 15 percent of all ovarian cancer risk [23], with other cancers also demonstrating increased prevalence in association with BRCA1 (uterine cervix and corpus, pancreas and colon) [24], [25] and BRCA2 (pancreas, stomach, gallbladder, bile ducts and malignant melanoma) [26].