However, after treatment with the DNA demethylating agent decitabine at 1 μM for 3 days, leading to mRNA reactivation in KMS-12-PE myeloma cells, similar DC-PCR results were obtained as in cells expressing CDKN2A (Normal Human Dermal Fibroblasts, NHDF) or PU.1 (RPMI 8226 myeloma cells) at baseline (Figures 1B and 2B). This evidence concerns the gene CDKN2A and plasma cell myeloma.